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These symptoms are generally transient, improving over a few weeks or months as the body adjusts to the medication

Some patients may start with Contrave due to cost or injection concerns, then transition to semaglutide if weight loss proves insufficient

Am J Physiol (Endocrinol Metab) 268:E 949955 Balks HJ, Holst JJ, von zur Mhlen A, Brabant G (1997) Rapid oscillations in plasma glucagon-like peptide-1 (GLP-1) in humans: cholinergic control of GLP-1 secretion via muscarinic receptors